Small ribosomal subunit protein eS21 (RPS21)

About Small ribosomal subunit protein eS21

Small ribosomal subunit protein eS21 (RPS21) is a protein from Homo sapiens identified by UniProt accession P63220, 83 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS21
UniProt accession	P63220
Gene	RPS21
Organism	Homo sapiens
Length	83 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (70)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
glioblastoma multiforme · score 0.15
aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63220-F1	alphafold	PREDICTED	95.48	—

Amino-acid sequence (83 residues)

MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF KTYAICGAIR RMGESDDSIL RLAKADGIVS KNF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards