Single-stranded DNA-binding protein 2 (SSBP2)

About Single-stranded DNA-binding protein 2

Single-stranded DNA-binding protein 2 (SSBP2) is a protein from Homo sapiens identified by UniProt accession P81877, 361 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.

Target properties

Protein name	Single-stranded DNA-binding protein 2
UniProt accession	P81877
Gene	SSBP2
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (144)

Diseases linked to this target (Open Targets).

lean body mass · score 0.47
body mass index · score 0.45
fat body mass · score 0.42
body weight · score 0.42
body fat percentage · score 0.40
bipolar disorder · score 0.38
platelet count · score 0.37
body height · score 0.37
platelet crit · score 0.33
self reported educational attainment · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P81877-F1	alphafold	PREDICTED	54.45	—

Amino-acid sequence (361 residues)

MYGKGKSNSS AVPSDSQARE KLALYVYEYL LHVGAQKSAQ TFLSEIRWEK NITLGEPPGF LHSWWCVFWD LYCAAPERRE TCEHSSEAKA FHDYSAAAAP SPVLGNIPPG DGMPVGPVPP GFFQPFMSPR YPGGPRPPLR IPNQALGGVP GSQPLLPSGM DPTRQQGHPN MGGPMQRMTP PRGMVPLGPQ NYGGAMRPPL NALGGPGMPG MNMGPGGGRP WPNPTNANSI PYSSASPGNY VGPPGGGGPP GTPIMPSPAD STNSGDNMYT LMNAVPPGPN RPNFPMGPGS DGPMGGLGGM ESHHMNGSLG SGDMDSISKN SPNNMSLSNQ PGTPRDDGEM GGNFLNPFQS ESYSPSMTMS V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards