Retinol-binding protein 5 (RBP5)

About Retinol-binding protein 5

Retinol-binding protein 5 (RBP5) is a protein from Homo sapiens identified by UniProt accession P82980, 135 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Retinol-binding protein 5
UniProt accession	P82980
Gene	RBP5
Organism	Homo sapiens
Length	135 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.25
platelet count · score 0.20
platelet crit · score 0.16
bone measurement · score 0.12
blood protein measurement · score 0.07
total blood protein measurement · score 0.05
complement C1s subcomponent measurement · score 0.03
serum IgG glycosylation measurement · score 0.02
hepatocellular carcinoma · score 0.02
neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P82980-F1	alphafold	PREDICTED	96.75	—

Amino-acid sequence (135 residues)

MPPNLTGYYR FVSQKNMEDY LQALNISLAV RKIALLLKPD KEIEHQGNHM TVRTLSTFRN YTVQFDVGVE FEEDLRSVDG RKCQTIVTWE EEHLVCVQKG EVPNRGWRHW LEGEMLYLEL TARDAVCEQV FRKVR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards