Small EDRK-rich factor 2 (SERF2)

About Small EDRK-rich factor 2

Small EDRK-rich factor 2 (SERF2) is a protein from Homo sapiens identified by UniProt accession P84101, 59 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Small EDRK-rich factor 2
UniProt accession	P84101
Gene	SERF2
Organism	Homo sapiens
Length	59 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.07
hemoglobin A1 measurement · score 0.07
type 2 diabetes mellitus · score 0.05
sphingomyelin measurement · score 0.05
susceptibility to urinary tract infection measurement · score 0.04
diastolic blood pressure · score 0.02
neuroblastoma · score 0.01
hepatocellular carcinoma · score 0.01
cancer · score 0.01
visceral Leishmaniasis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P84101-F1	alphafold	PREDICTED	81.40	—

Amino-acid sequence (59 residues)

MTRGNQRELA RQKNMKKQSD SVKGKRRDDG LSAAARKQRD SEIMQQKQKK ANEKKEEPK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards