About Serine/arginine-rich splicing factor 3
Serine/arginine-rich splicing factor 3 (SRSF3) is a protein
from Homo sapiens identified by UniProt accession
P84103, 164 residues long.
MolForge cross-references it against 0 known binders and
200 disease associations.
Target properties
| Protein name | Serine/arginine-rich splicing factor 3 |
|---|
| UniProt accession | P84103 |
|---|
| Gene | SRSF3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 164 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (200)
Diseases linked to this target (Open Targets).
- Hepatobiliary Neoplasm · score 0.37
- bile duct carcinoma · score 0.37
- carcinoma of liver and intrahepatic biliary tract · score 0.37
- bile duct adenocarcinoma · score 0.37
- mean corpuscular volume · score 0.33
- hepatocellular carcinoma · score 0.30
- mean reticulocyte volume · score 0.30
- open-angle glaucoma · score 0.29
- cup-to-disc ratio measurement · score 0.29
- hemoglobin measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P84103-F1 | alphafold | PREDICTED | 60.74 | — |
Amino-acid sequence (164 residues)
MHRDSCPLDC KVYVGNLGNN GNKTELERAF GYYGPLRSVW VARNPPGFAF VEFEDPRDAA DAVRELDGRT LCGCRVRVEL SNGEKRSRNR GPPPSWGRRP RDDYRRRSPP PRRRSPRRRS FSRSRSRSLS RDRRRERSLS RERNHKPSRS FSRSRSRSRS NERK
Explore Serine/arginine-rich splicing factor 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets