About Tumor necrosis factor-inducible gene 6 protein
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) is a protein
from Homo sapiens identified by UniProt accession
P98066, 277 residues long.
MolForge cross-references it against 0 known binders and
311 disease associations.
Target properties
| Protein name | Tumor necrosis factor-inducible gene 6 protein |
|---|
| UniProt accession | P98066 |
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| Gene | TNFAIP6 |
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| Organism | Homo sapiens |
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| Length | 277 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (311)
Diseases linked to this target (Open Targets).
- tumor necrosis factor-inducible gene 6 protein measurement · score 0.31
- blood protein measurement · score 0.31
- creatinine measurement · score 0.31
- cystatin C measurement · score 0.30
- neurodegenerative disease · score 0.26
- protein measurement · score 0.22
- subarachnoid hemorrhage · score 0.10
- cortical surface area measurement · score 0.09
- Rheumatoid arthritis · score 0.09
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P98066-F1 | alphafold | PREDICTED | 81.15 | — |
Amino-acid sequence (277 residues)
MIILIYLFLL LWEDTQGWGF KDGIFHNSIW LERAAGVYHR EARSGKYKLT YAEAKAVCEF EGGHLATYKQ LEAARKIGFH VCAAGWMAKG RVGYPIVKPG PNCGFGKTGI IDYGIRLNRS ERWDAYCYNP HAKECGGVFT DPKQIFKSPG FPNEYEDNQI CYWHIRLKYG QRIHLSFLDF DLEDDPGCLA DYVEIYDSYD DVHGFVGRYC GDELPDDIIS TGNVMTLKFL SDASVTAGGF QIKYVAMDPV SKSSQGKNTS TTSTGNKNFL AGRFSHL
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