Tumor necrosis factor receptor superfamily member…

About Tumor necrosis factor receptor superfamily member 17

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is a protein from Homo sapiens identified by UniProt accession Q02223, 184 residues long. MolForge cross-references it against 0 known binders and 387 disease associations.

Target properties

Protein name	Tumor necrosis factor receptor superfamily member 17
UniProt accession	Q02223
Gene	TNFRSF17
Organism	Homo sapiens
Length	184 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (4)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (387)

Diseases linked to this target (Open Targets).

multiple myeloma · score 0.62
neoplasm · score 0.49
neurodegenerative disease · score 0.38
monoclonal gammopathy · score 0.37
plasma cell neoplasm · score 0.37
pancreatic carcinoma · score 0.37
immune system disease · score 0.37
cardiovascular disease · score 0.37
cutaneous melanoma · score 0.37
vascular disease · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02223-F1	alphafold	PREDICTED	64.96	—

Amino-acid sequence (184 residues)

MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNAILWTCL GLSLIISLAV FVLMFLLRKI NSEPLKDEFK NTGSGLLGMA NIDLEKSRTG DEIILPRGLE YTVEECTCED CIKSKPKVDS DHCFPLPAME EGATILVTTK TNDYCKSLPA ALSATEIEKS ISAR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)