About Single-stranded DNA-binding protein, mitochondrial
Single-stranded DNA-binding protein, mitochondrial (SSBP1) is a protein
from Homo sapiens identified by UniProt accession
Q04837, 148 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Single-stranded DNA-binding protein, mitochondrial |
|---|
| UniProt accession | Q04837 |
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| Gene | SSBP1 |
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| Organism | Homo sapiens |
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| Length | 148 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- optic atrophy 13 with retinal and foveal abnormalities · score 0.74
- neurodegenerative disease · score 0.49
- cone-rod dystrophy · score 0.34
- Cone rod dystrophy · score 0.34
- genetic disorder · score 0.17
- venous thromboembolism · score 0.15
- sensory perception of bitter taste · score 0.08
- glioblastoma multiforme · score 0.07
- gonorrhea · score 0.05
- blood protein measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q04837-F1 | alphafold | PREDICTED | 83.72 | — |
Amino-acid sequence (148 residues)
MFRRPVLQVL RQFVRHESET TTSLVLERSL NRVHLLGRVG QDPVLRQVEG KNPVTIFSLA TNEMWRSGDS EVYQLGDVSQ KTTWHRISVF RPGLRDVAYQ YVKKGSRIYL EGKIDYGEYM DKNNVRRQAT TIIADNIIFL SDQTKEKE
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