About Sulfotransferase 2A1
Sulfotransferase 2A1 (SULT2A1) is a protein
from Homo sapiens identified by UniProt accession
Q06520, 285 residues long.
MolForge cross-references it against 0 known binders and
260 disease associations.
Target properties
| Protein name | Sulfotransferase 2A1 |
|---|
| UniProt accession | Q06520 |
|---|
| Gene | SULT2A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 285 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (260)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.45
- cholelithiasis · score 0.42
- blood metabolite measurement · score 0.42
- serum metabolite measurement · score 0.39
- triglyceride measurement · score 0.36
- alkaline phosphatase measurement · score 0.36
- gallbladder disease · score 0.33
- gallstones · score 0.32
- dehydroepiandrosterone sulphate measurement · score 0.32
- urinary metabolite measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q06520-F1 | alphafold | PREDICTED | 95.48 | — |
Amino-acid sequence (285 residues)
MSDDFLWFEG IAFPTMGFRS ETLRKVRDEF VIRDEDVIIL TYPKSGTNWL AEILCLMHSK GDAKWIQSVP IWERSPWVES EIGYTALSET ESPRLFSSHL PIQLFPKSFF SSKAKVIYLM RNPRDVLVSG YFFWKNMKFI KKPKSWEEYF EWFCQGTVLY GSWFDHIHGW MPMREEKNFL LLSYEELKQD TGRTIEKICQ FLGKTLEPEE LNLILKNSSF QSMKENKMSN YSLLSVDYVV DKAQLLRKGV SGDWKNHFTV AQAEDFDKLF QEKMADLPRE LFPWE
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