About Tumor necrosis factor receptor superfamily member 9
Tumor necrosis factor receptor superfamily member 9 (TNFRSF9) is a protein
from Homo sapiens identified by UniProt accession
Q07011, 255 residues long.
MolForge cross-references it against 0 known binders and
605 disease associations.
Target properties
| Protein name | Tumor necrosis factor receptor superfamily member 9 |
|---|
| UniProt accession | Q07011 |
|---|
| Gene | TNFRSF9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (605)
Diseases linked to this target (Open Targets).
- hair color · score 0.27
- rheumatoid arthritis · score 0.24
- ulcerative colitis · score 0.24
- body weight · score 0.20
- pancreatic adenocarcinoma · score 0.19
- genetic disorder · score 0.18
- eosinophil percentage of leukocytes · score 0.18
- fat body mass · score 0.15
- lean body mass · score 0.14
- protein measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07011-F1 | alphafold | PREDICTED | 81.98 | — |
Amino-acid sequence (255 residues)
MGNSCYNIVA TLLLVLNFER TRSLQDPCSN CPAGTFCDNN RNQICSPCPP NSFSSAGGQR TCDICRQCKG VFRTRKECSS TSNAECDCTP GFHCLGAGCS MCEQDCKQGQ ELTKKGCKDC CFGTFNDQKR GICRPWTNCS LDGKSVLVNG TKERDVVCGP SPADLSPGAS SVTPPAPARE PGHSPQIISF FLALTSTALL FLLFFLTLRF SVVKRGRKKL LYIFKQPFMR PVQTTQEEDG CSCRFPEEEE GGCEL
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