About Zinc finger protein 763
Zinc finger protein 763 (ZNF763) is a protein
from Homo sapiens identified by UniProt accession
Q0D2J5, 394 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Zinc finger protein 763 |
|---|
| UniProt accession | Q0D2J5 |
|---|
| Gene | ZNF763 |
|---|
| Organism | Homo sapiens |
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| Length | 394 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- mean corpuscular volume · score 0.25
- Alzheimer disease · score 0.22
- lysosomal storage disease · score 0.22
- Parkinson disease · score 0.22
- multiple sclerosis · score 0.22
- mean corpuscular hemoglobin concentration · score 0.18
- mean corpuscular hemoglobin · score 0.09
- Down syndrome · score 0.04
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0D2J5-F1 | alphafold | PREDICTED | 67.23 | — |
Amino-acid sequence (394 residues)
MDPVACEDVA VNFTQEEWAL LDISQRKLYR EVMLETFRNL TSIGKKWKDQ NIEYEYQNPR RNFRSLIEGN VNEIKEDSHC GETFTQVPDD RLNFQEKKAS PEAKSCDNFV CGEVGIGNSS FNMNIRGDIG HKAYEYQDYA PKPYKCQQPK KAFRYHPSFR TQERNHTGEK PYACKECGKT FISHSGIRRR MVMHSGDGPY KCKFCGKAVH CLRLYLIHER THTGEKPYEC KQCVKSFSYS ATHRIHERTH TGEKPYECQQ CGKAFHSSSS FQAHKRTHTG GKPYECKQCG KSFSWCHSFQ IHERTHTGEK PCECSKCNKA FRSYRSYLRH KRSHTGEKPY QCKECRKAFT YPSSLRRHER THSAKKPYEC KQCGKALSYK FSNTPKNALW RKTL
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