Sodium/bile acid cotransporter 7 (SLC10A7)

About Sodium/bile acid cotransporter 7

Sodium/bile acid cotransporter 7 (SLC10A7) is a protein from Homo sapiens identified by UniProt accession Q0GE19, 340 residues long. MolForge cross-references it against 0 known binders and 364 disease associations.

Target properties

Protein name	Sodium/bile acid cotransporter 7
UniProt accession	Q0GE19
Gene	SLC10A7
Organism	Homo sapiens
Length	340 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (364)

Diseases linked to this target (Open Targets).

short stature, amelogenesis imperfecta, and skeletal dysplasia with scoliosis · score 0.71
body mass index · score 0.45
Skeletal dysplasia · score 0.38
skeletal dysplasia · score 0.38
scoliosis · score 0.37
Short stature · score 0.37
chronotype measurement · score 0.32
body height · score 0.31
bipolar disorder · score 0.30
anorexia nervosa · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q0GE19-F1	alphafold	PREDICTED	85.13	—

Amino-acid sequence (340 residues)

MRLLERMRKD WFMVGIVLAI AGAKLEPSIG VNGGPLKPEI TVSYIAVATI FFNSGLSLKT EELTSALVHL KLHLFIQIFT LAFFPATIWL FLQLLSITPI NEWLLKGLQT VGCMPPPVSS AVILTKAVGG NEAAAIFNSA FGSFLGIVIT PLLLLLFLGS SSSVPFTSIF SQLFMTVVVP LIIGQIVRRY IKDWLERKKP PFGAISSSVL LMIIYTTFCD TFSNPNIDLD KFSLVLILFI IFSIQLSFML LTFIFSTRNN SGFTPADTVA IIFCSTHKSL TLGIPMLKIV FAGHEHLSLI SVPLLIYHPA QILLGSVLVP TIKSWMVSRQ KGVKLTRPTV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards