About Syncollin
Syncollin (SYCN) is a protein
from Homo sapiens identified by UniProt accession
Q0VAF6, 134 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Syncollin |
|---|
| UniProt accession | Q0VAF6 |
|---|
| Gene | SYCN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 134 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- Hyperlipoproteinemia type 1 · score 0.06
- chronic pancreatitis · score 0.05
- hereditary chronic pancreatitis · score 0.04
- bronchiectasis with or without elevated sweat chloride 1 · score 0.04
- Bronchiectasis · score 0.04
- GCGR-related hyperglucagonemia · score 0.04
- hyperinsulinemic hypoglycemia, familial, 2 · score 0.04
- gallbladder disease · score 0.03
- pancreatic agenesis 2 · score 0.03
- benign recurrent intrahepatic cholestasis type 1 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0VAF6-F1 | alphafold | PREDICTED | 87.73 | — |
Amino-acid sequence (134 residues)
MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE NCCGGAELSL ESGADLPYLP SNWANTASSL VVAPRCELTV WSRQGKAGKT HKFSAGTYPR LEEYRRGILG DWSNAISALY CRCS
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