About Transmembrane protein 267
Transmembrane protein 267 (TMEM267) is a protein
from Homo sapiens identified by UniProt accession
Q0VDI3, 215 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Transmembrane protein 267 |
|---|
| UniProt accession | Q0VDI3 |
|---|
| Gene | TMEM267 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 215 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- forced expiratory volume · score 0.30
- FEV/FVC ratio · score 0.26
- vital capacity · score 0.20
- Red cell distribution width · score 0.19
- mathematical ability · score 0.18
- self reported educational attainment · score 0.18
- reticulocyte count · score 0.17
- reticulocyte measurement · score 0.15
- apolipoprotein A 1 measurement · score 0.14
- eosinophil count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0VDI3-F1 | alphafold | PREDICTED | 89.77 | — |
Amino-acid sequence (215 residues)
MASETEKTHA LLQTCSTESL ISSLGLGAFC LVADRLLQFS TIQQNDWLRA LSDNAVHCVI GMWSWAVVTG IKKKTDFGEI ILAGFLASVI DVDHFFLAGS MSLKAALTLP RRPFLHCSTV IPVVVLTLKF TMHLFKLKDS WCFLPWMLFI SWTSHHIRDG IRHGLWICPF GKTSPLPFWL YVIITSSLPH ICSFVMYLTG TRQMMSSKHG VRIDV
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