About Oviduct-specific glycoprotein
Oviduct-specific glycoprotein (OVGP1) is a protein
from Homo sapiens identified by UniProt accession
Q12889, 678 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Oviduct-specific glycoprotein |
|---|
| UniProt accession | Q12889 |
|---|
| Gene | OVGP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 678 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.25
- squamous cell lung carcinoma · score 0.18
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.17
- breast adenocarcinoma · score 0.16
- glioblastoma multiforme · score 0.15
- head and neck squamous cell carcinoma · score 0.13
- neoplasm · score 0.06
- cholangiocarcinoma · score 0.04
- blood protein measurement · score 0.04
- neutrophil count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q12889-F1 | alphafold | PREDICTED | 68.84 | — |
Amino-acid sequence (678 residues)
MWKLLLWVGL VLVLKHHDGA AHKLVCYFTN WAHSRPGPAS ILPHDLDPFL CTHLIFAFAS MNNNQIVAKD LQDEKILYPE FNKLKERNRE LKTLLSIGGW NFGTSRFTTM LSTFANREKF IASVISLLRT HDFDGLDLFF LYPGLRGSPM HDRWTFLFLI EELLFAFRKE ALLTMRPRLL LSAAVSGVPH IVQTSYDVRF LGRLLDFINV LSYDLHGSWE RFTGHNSPLF SLPEDPKSSA YAMNYWRKLG APSEKLIMGI PTYGRTFRLL KASKNGLQAR AIGPASPGKY TKQEGFLAYF EICSFVWGAK KHWIDYQYVP YANKGKEWVG YDNAISFSYK AWFIRREHFG GAMVWTLDMD DVRGTFCGTG PFPLVYVLND ILVRAEFSST SLPQFWLSSA VNSSSTDPER LAVTTAWTTD SKILPPGGEA GVTEIHGKCE NMTITPRGTT VTPTKETVSL GKHTVALGEK TEITGAMTMT SVGHQSMTPG EKALTPVGHQ SVTTGQKTLT SVGYQSVTPG EKTLTPVGHQ SVTPVSHQSV SPGGTTMTPV HFQTETLRQN TVAPRRKAVA REKVTVPSRN ISVTPEGQTM PLRGENLTSE VGTHPRMGNL GLQMEAENRM MLSSSPVIQL PEQTPLAFDN RFVPIYGNHS SVNSVTPQTS PLSLKKEIPE NSAVDEEA
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