MAL-like protein (MALL)

About MAL-like protein

MAL-like protein (MALL) is a protein from Homo sapiens identified by UniProt accession Q13021, 153 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	MAL-like protein
UniProt accession	Q13021
Gene	MALL
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
Senior-Loken syndrome · score 0.33
nephronophthisis 1 · score 0.33
cone dystrophy · score 0.26
neoplasm · score 0.08
esophageal squamous cell carcinoma · score 0.03
cancer · score 0.03
squamous cell carcinoma · score 0.02
cervical squamous cell carcinoma · score 0.01
Neoplasm of the lung · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13021-F1	alphafold	PREDICTED	89.91	—

Amino-acid sequence (153 residues)

MASPDPPATS YAPSDVPSGV ALFLTIPFAF FLPELIFGFL VWTMVAATHI VYPLLQGWVM YVSLTSFLIS LMFLLSYLFG FYKRFESWRV LDSLYHGTTG ILYMSAAVLQ VHATIVSEKL LDPRIYYINS AASFFAFIAT LLYILHAFSI YYH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards