Protein Red (IK)

About Protein Red

Protein Red (IK) is a protein from Homo sapiens identified by UniProt accession Q13123, 557 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.

Target properties

Protein name	Protein Red
UniProt accession	Q13123
Gene	IK
Organism	Homo sapiens
Length	557 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (88)

Diseases linked to this target (Open Targets).

mitochondrial complex I deficiency · score 0.48
genetic disorder · score 0.16
neurodegenerative disease · score 0.16
Leigh syndrome · score 0.12
systolic blood pressure · score 0.08
Fuchs endothelial corneal dystrophy · score 0.05
Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
depressive symptom measurement · score 0.04
lattice corneal dystrophy type I · score 0.04
X-linked endothelial corneal dystrophy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13123-F1	alphafold	PREDICTED	68.12	—

Amino-acid sequence (557 residues)

MPERDSEPFS NPLAPDGHDV DDPHSFHQSK LTNEDFRKLL MTPRAAPTSA PPSKSRHHEM PREYNEDEDP AARRRKKKSY YAKLRQQEIE RERELAEKYR DRAKERRDGV NKDYEETELI STTANYRAVG PTAEADKSAA EKRRQLIQES KFLGGDMEHT HLVKGLDFAL LQKVRAEIAS KEKEEEELME KPQKETKKDE DPENKIEFKT RLGRNVYRML FKSKAYERNE LFLPGRMAYV VDLDDEYADT DIPTTLIRSK ADCPTMEAQT TLTTNDIVIS KLTQILSYLR QGTRNKKLKK KDKGKLEEKK PPEADMNIFE DIGDYVPSTT KTPRDKERER YRERERDRER DRDRDRERER ERDRERERER DREREEEKKR HSYFEKPKVD DEPMDVDKGP GSTKELIKSI NEKFAGSAGW EGTESLKKPE DKKQLGDFFG MSNSYAECYP ATMDDMAVDS DEEVDYSKMD QGNKKGPLGR WDFDTQEEYS EYMNNKEALP KAAFQYGIKM SEGRKTRRFK ETNDKAELDR QWKKISAIIE KRKKMEADGV EVKRPKY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards