Natural killer cells antigen CD94 (KLRD1)

About Natural killer cells antigen CD94

Natural killer cells antigen CD94 (KLRD1) is a protein from Homo sapiens identified by UniProt accession Q13241, 179 residues long. MolForge cross-references it against 0 known binders and 240 disease associations.

Target properties

Protein name	Natural killer cells antigen CD94
UniProt accession	Q13241
Gene	KLRD1
Organism	Homo sapiens
Length	179 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (240)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.23
neoplasm · score 0.09
celiac disease · score 0.07
graft versus host disease · score 0.07
influenza · score 0.05
Systemic lupus erythematosus · score 0.04
infection · score 0.04
infect · score 0.04
viral disease · score 0.04
Rheumatoid arthritis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13241-F1	alphafold	PREDICTED	87.56	—

Amino-acid sequence (179 residues)

MAVFKTTLWR LISGTLGIIC LSLMSTLGIL LKNSFTKLSI EPAFTPGPNI ELQKDSDCCS CQEKWVGYRC NCYFISSEQK TWNESRHLCA SQKSSLLQLQ NTDELDFMSS SQQFYWIGLS YSEEHTAWLW ENGSALSQYL FPSFETFNTK NCIAYNPNGN ALDESCEDKN RYICKQQLI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards