About Microfibrillar-associated protein 5
Microfibrillar-associated protein 5 (MFAP5) is a protein
from Homo sapiens identified by UniProt accession
Q13361, 173 residues long.
MolForge cross-references it against 0 known binders and
149 disease associations.
Target properties
| Protein name | Microfibrillar-associated protein 5 |
|---|
| UniProt accession | Q13361 |
|---|
| Gene | MFAP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 173 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (149)
Diseases linked to this target (Open Targets).
- familial thoracic aortic aneurysm and aortic dissection · score 0.66
- Rare disease with thoracic aortic aneurysm and aortic dissection · score 0.33
- thoracic aortic aneurysm · score 0.27
- lung adenocarcinoma · score 0.21
- Abnormality of the cardiovascular system · score 0.19
- breast adenocarcinoma · score 0.18
- endometrial cancer · score 0.14
- connective tissue disease · score 0.12
- head and neck squamous cell carcinoma · score 0.12
- neoplasm · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13361-F1 | alphafold | PREDICTED | 64.96 | — |
Amino-acid sequence (173 residues)
MSLLGPKVLL FLAAFIITSD WIPLGVNSQR GDDVTQATPE TFTEDPNLVN DPATDETVLA VLADIAPSTD DLASLSEKNT TAECWDEKFT CTRLYSVHRP VKQCIHQLCF TSLRRMYIVN KEICSRLVCK EHEAMKDELC RQMAGLPPRR LRRSNYFRLP PCENVDLQRP NGL
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