Eukaryotic translation initiation factor 4E-binding…

About Eukaryotic translation initiation factor 4E-binding protein 2

Eukaryotic translation initiation factor 4E-binding protein 2 (EIF4EBP2) is a protein from Homo sapiens identified by UniProt accession Q13542, 120 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Eukaryotic translation initiation factor 4E-binding protein 2
UniProt accession	Q13542
Gene	EIF4EBP2
Organism	Homo sapiens
Length	120 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

insulin resistance · score 0.04
Insulin resistance · score 0.03
Cerebral ischemia · score 0.02
viral disease · score 0.01
neoplasm · score 0.01
Autism · score 0.01
infection · score 0.01
infect · score 0.01
Obesity · score 0.01
sarcopenia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13542-F1	alphafold	PREDICTED	76.01	—

Amino-acid sequence (120 residues)

MSSSAGSGHQ PSQSRAIPTR TVAISDAAQL PHDYCTTPGG TLFSTTPGGT RIIYDRKFLL DRRNSPMAQT PPCHLPNIPG VTSPGTLIED SKVEVNNLNN LNNHDRKHAV GDDAQFEMDI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Eukaryotic translation initiation factor 4E-binding protein 2 (EIF4EBP2)