Angio-associated migratory cell protein (AAMP)

About Angio-associated migratory cell protein

Angio-associated migratory cell protein (AAMP) is a protein from Homo sapiens identified by UniProt accession Q13685, 434 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Angio-associated migratory cell protein
UniProt accession	Q13685
Gene	AAMP
Organism	Homo sapiens
Length	434 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

ulcerative colitis · score 0.20
Red cell distribution width · score 0.20
monocyte count · score 0.19
neutrophil count · score 0.18
systolic blood pressure · score 0.18
reticulocyte count · score 0.17
leukocyte count · score 0.15
vital capacity · score 0.15
basophil count · score 0.15
cholelithiasis · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13685-F1	alphafold	PREDICTED	84.57	—

Amino-acid sequence (434 residues)

MESESESGAA ADTPPLETLS FHGDEEIIEV VELDPGPPDP DDLAQEMEDV DFEEEEEEEG NEEGWVLEPQ EGVVGSMEGP DDSEVTFALH SASVFCVSLD PKTNTLAVTG GEDDKAFVWR LSDGELLFEC AGHKDSVTCA GFSHDSTLVA TGDMSGLLKV WQVDTKEEVW SFEAGDLEWM EWHPRAPVLL AGTADGNTWM WKVPNGDCKT FQGPNCPATC GRVLPDGKRA VVGYEDGTIR IWDLKQGSPI HVLKGTEGHQ GPLTCVAANQ DGSLILTGSV DCQAKLVSAT TGKVVGVFRP ETVASQPSLG EGEESESNSV ESLGFCSVMP LAAVGYLDGT LAIYDLATQT LRHQCQHQSG IVQLLWEAGT AVVYTCSLDG IVRLWDARTG RLLTDYRGHT AEILDFALSK DASLVVTTSG DHKAKVFCVQ RPDR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards