About Integrin alpha-9
Integrin alpha-9 (ITGA9) is a protein
from Homo sapiens identified by UniProt accession
Q13797, 1035 residues long.
MolForge cross-references it against 0 known binders and
148 disease associations.
Target properties
| Protein name | Integrin alpha-9 |
|---|
| UniProt accession | Q13797 |
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| Gene | ITGA9 |
|---|
| Organism | Homo sapiens |
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| Length | 1035 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (148)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.46
- heel bone mineral density · score 0.43
- BMI-adjusted waist-hip ratio · score 0.42
- pulse pressure measurement · score 0.41
- platelet count · score 0.41
- waist-hip ratio · score 0.34
- BMI-adjusted hip circumference · score 0.32
- phospholipid measurement · score 0.32
- sporadic amyotrophic lateral sclerosis · score 0.27
- PR interval · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13797-F1 | alphafold | PREDICTED | 85.08 | — |
Amino-acid sequence (1035 residues)
MGGPAAPRGA GRLRALLLAL VVAGIPAGAY NLDPQRPVHF QGPADSFFGY AVLEHFHDNT RWVLVGAPKA DSKYSPSVKS PGAVFKCRVH TNPDRRCTEL DMARGKNRGT SCGKTCREDR DDEWMGVSLA RQPKADGRVL ACAHRWKNIY YEADHILPHG FCYIIPSNLQ AKGRTLIPCY EEYKKKYGEE HGSCQAGIAG FFTEELVVMG APGSFYWAGT IKVLNLTDNT YLKLNDEVIM NRRYTYLGYA VTAGHFSHPS TIDVVGGAPQ DKGIGKVYIF RADRRSGTLI KIFQASGKKM GSYFGSSLCA VDLNGDGLSD LLVGAPMFSE IRDEGQVTVY INRGNGALEE QLALTGDGAY NAHFGESIAS LDDLDNDGFP DVAIGAPKED DFAGAVYIYH GDAGGIVPQY SMKLSGQKIN PVLRMFGQSI SGGIDMDGNG YPDVTVGAFM SDSVVLLRAR PVITVDVSIF LPGSINITAP QCHDGQQPVN CLNVTTCFSF HGKHVPGEIG LNYVLMADVA KKEKGQMPRV YFVLLGETMG QVTEKLQLTY MEETCRHYVA HVKRRVQDVI SPIVFEAAYS LSEHVTGEEE RELPPLTPVL RWKKGQKIAQ KNQTVFERNC RSEDCAADLQ LQGKLLLSSM DEKTLYLALG AVKNISLNIS ISNLGDDAYD ANVSFNVSRE LFFINMWQKE EMGISCELLE SDFLKCSVGF PFMRSKSKYE FSVIFDTSHL SGEEEVLSFI VTAQSGNTER SESLHDNTLV LMVPLMHEVD TSITGIMSPT SFVYGESVDA ANFIQLDDLE CHFQPINITL QVYNTGPSTL PGSSVSISFP NRLSSGGAEM FHVQEMVVGQ EKGNCSFQKN PTPCIIPQEQ ENIFHTIFAF FTKSGRKVLD CEKPGISCLT AHCNFSALAK EESRTIDIYM LLNTEILKKD SSSVIQFMSR AKVKVDPALR VVEIAHGNPE EVTVVFEALH NLEPRGYVVG WIIAISLLVG ILIFLLLAVL LWKMGFFRRR YKEIIEAEKN RKENEDSWDW VQKNQ
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