About Protein Tob2
Protein Tob2 (TOB2) is a protein
from Homo sapiens identified by UniProt accession
Q14106, 344 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Protein Tob2 |
|---|
| UniProt accession | Q14106 |
|---|
| Gene | TOB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 344 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- eosinophil count · score 0.12
- body fat percentage · score 0.11
- asthma · score 0.10
- fat body mass · score 0.10
- hypothyroidism · score 0.08
- alcohol consumption measurement · score 0.08
- diet measurement · score 0.07
- respiratory system disease · score 0.07
- mathematical ability · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14106-F1 | alphafold | PREDICTED | 64.75 | — |
Amino-acid sequence (344 residues)
MQLEIKVALN FIISYLYNKL PRRRADLFGE ELERLLKKKY EGHWYPEKPL KGSGFRCVHI GEMVDPVVEL AAKRSGLAVE DVRANVPEEL SVWIDPFEVS YQIGEKGAVK VLYLDDSEGC GAPELDKEIK SSFNPDAQVF VPIGSQDSSL SNSPSPSFGQ SPSPTFIPRS AQPITFTTAS FAATKFGSTK MKKGGGAASG GGVASSGAGG QQPPQQPRMA RSPTNSLLKH KSLSLSMHSL NFITANPAPQ SQLSPNAKEF VYNGGGSPSL FFDAADGQGS GTPGPFGGSG AGTCNSSSFD MAQVFGGGAN SLFLEKTPFV EGLSYNLNTM QYPSQQFQPV VLAN
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