About Lymphocyte antigen 6D
Lymphocyte antigen 6D (LY6D) is a protein
from Homo sapiens identified by UniProt accession
Q14210, 128 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Lymphocyte antigen 6D |
|---|
| UniProt accession | Q14210 |
|---|
| Gene | LY6D |
|---|
| Organism | Homo sapiens |
|---|
| Length | 128 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.11
- calcium measurement · score 0.08
- attention deficit-hyperactivity disorder 8 · score 0.07
- attention deficit hyperactivity disorder · score 0.07
- schizophrenia 15 · score 0.07
- non-small cell lung carcinoma · score 0.05
- non-alcoholic fatty liver disease · score 0.05
- Phelan-McDermid syndrome · score 0.05
- X-linked non-syndromic intellectual disability · score 0.04
- Crohn's disease · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14210-F1 | alphafold | PREDICTED | 79.27 | — |
Amino-acid sequence (128 residues)
MRTALLLLAA LAVATGPALT LRCHVCTSSS NCKHSVVCPA SSRFCKTTNT VEPLRGNLVK KDCAESCTPS YTLQGQVSSG TSSTQCCQED LCNEKLHNAA PTRTALAHSA LSLGLALSLL AVILAPSL
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