About Fibroblast growth factor-binding protein 1
Fibroblast growth factor-binding protein 1 (FGFBP1) is a protein
from Homo sapiens identified by UniProt accession
Q14512, 234 residues long.
MolForge cross-references it against 0 known binders and
89 disease associations.
Target properties
| Protein name | Fibroblast growth factor-binding protein 1 |
|---|
| UniProt accession | Q14512 |
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| Gene | FGFBP1 |
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| Organism | Homo sapiens |
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| Length | 234 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (89)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.31
- lung adenocarcinoma · score 0.23
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- cutaneous melanoma · score 0.18
- neoplasm · score 0.07
- squamous cell carcinoma · score 0.06
- triple-negative breast cancer · score 0.05
- oral squamous cell carcinoma · score 0.05
- breast carcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14512-F1 | alphafold | PREDICTED | 73.61 | — |
Amino-acid sequence (234 residues)
MKICSLTLLS FLLLAAQVLL VEGKKKVKNG LHSKVVSEQK DTLGNTQIKQ KSRPGNKGKF VTKDQANCRW AATEQEEGIS LKVECTQLDH EFSCVFAGNP TSCLKLKDER VYWKQVARNL RSQKDICRYS KTAVKTRVCR KDFPESSLKL VSSTLFGNTK PRKEKTEMSP REHIKGKETT PSSLAVTQTM ATKAPECVED PDMANQRKTA LEFCGETWSS LCTFFLSIVQ DTSC
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