About TNFAIP3-interacting protein 1
TNFAIP3-interacting protein 1 (TNIP1) is a protein
from Homo sapiens identified by UniProt accession
Q15025, 636 residues long.
MolForge cross-references it against 0 known binders and
483 disease associations.
Target properties
| Protein name | TNFAIP3-interacting protein 1 |
|---|
| UniProt accession | Q15025 |
|---|
| Gene | TNIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 636 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (483)
Diseases linked to this target (Open Targets).
- psoriasis · score 0.37
- systemic lupus erythematosus · score 0.36
- eosinophil count · score 0.36
- systemic scleroderma · score 0.33
- C-reactive protein measurement · score 0.31
- eosinophil percentage of leukocytes · score 0.30
- lymphocyte count · score 0.30
- psoriasis vulgaris · score 0.28
- psoriatic arthritis · score 0.27
- type 2 diabetes mellitus · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15025-F1 | alphafold | PREDICTED | 70.94 | — |
Amino-acid sequence (636 residues)
MEGRGPYRIY DPGGSVPSGE ASAAFERLVK ENSRLKEKMQ GIKMLGELLE ESQMEATRLR QKAEELVKDN ELLPPPSPSL GSFDPLAELT GKDSNVTASP TAPACPSDKP APVQKPPSSG TSSEFEVVTP EEQNSPESSS HANAMALGPL PREDGNLMLH LQRLETTLSV CAEEPDHGQL FTHLGRMALE FNRLASKVHK NEQRTSILQT LCEQLRKENE ALKAKLDKGL EQRDQAAERL REENLELKKL LMSNGNKEGA SGRPGSPKME GTGKKAVAGQ QQASVTAGKV PEVVALGAAE KKVKMLEQQR SELLEVNKQW DQHFRSMKQQ YEQKITELRQ KLADLQKQVT DLEAEREQKQ RDFDRKLLLA KSKIEMEETD KEQLTAEAKE LRQKVKYLQD QLSPLTRQRE YQEKEIQRLN KALEEALSIQ TPPSSPPTAF GSPEGAGALL RKQELVTQNE LLKQQVKIFE EDFQRERSDR ERMNEEKEEL KKQVEKLQAQ VTLSNAQLKA FKDEEKAREA LRQQKRKAKA SGERYHVEPH PEHLCGAYPY AYPPMPAMVP HHGFEDWSQI RYPPPPMAME HPPPLPNSRL FHLPEYTWRL PCGGVRNPNQ SSQVMDPPTA RPTEPESPKN DREGPQ
Explore TNFAIP3-interacting protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets