Mitochondrial inner membrane protein OXA1L (OXA1L)

About Mitochondrial inner membrane protein OXA1L

Mitochondrial inner membrane protein OXA1L (OXA1L) is a protein from Homo sapiens identified by UniProt accession Q15070, 435 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Mitochondrial inner membrane protein OXA1L
UniProt accession	Q15070
Gene	OXA1L
Organism	Homo sapiens
Length	435 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

mitochondrial disease · score 0.42
lysinuric protein intolerance · score 0.33
Familial prostate cancer · score 0.11
prostate cancer · score 0.11
myoepithelial tumor · score 0.11
prostate carcinoma · score 0.11
intraocular pressure measurement · score 0.10
heart failure · score 0.05
Duane retraction syndrome · score 0.04
overweight body mass index status · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15070-F1	alphafold	PREDICTED	73.75	—

Amino-acid sequence (435 residues)

MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL LFPAAPCCCR PHYLFLAASG PRSLSTSAIS FAEVQVQAPP VVAATPSPTA VPEVASGETA DVVQTAAEQS FAELGLGSYT PVGLIQNLLE FMHVDLGLPW WGAIAACTVF ARCLIFPLIV TGQREAARIH NHLPEIQKFS SRIREAKLAG DHIEYYKASS EMALYQKKHG IKLYKPLILP VTQAPIFISF FIALREMANL PVPSLQTGGL WWFQDLTVSD PIYILPLAVT ATMWAVLELG AETGVQSSDL QWMRNVIRMM PLITLPITMH FPTAVFMYWL SSNLFSLVQV SCLRIPAVRT VLKIPQRVVH DLDKLPPREG FLESFKKGWK NAEMTRQLRE REQRMRNQLE LAARGPLRQT FTHNPLLQPG KDNPPNIPSS SSKPKSKYPW HDTLG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards