About Serine/threonine-protein kinase 38
Serine/threonine-protein kinase 38 (STK38) is a protein
from Homo sapiens identified by UniProt accession
Q15208, 465 residues long.
MolForge cross-references it against 0 known binders and
147 disease associations.
Target properties
| Protein name | Serine/threonine-protein kinase 38 |
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| UniProt accession | Q15208 |
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| Gene | STK38 |
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| Organism | Homo sapiens |
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| Length | 465 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (3)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (147)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.40
- platelet count · score 0.26
- neurodegenerative disease · score 0.25
- retinopathy · score 0.12
- optic choroid disorder · score 0.12
- bladder exstrophy · score 0.12
- platelet component distribution width · score 0.12
- dilated cardiomyopathy · score 0.11
- monocyte percentage of leukocytes · score 0.10
- airway imaging measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15208-F1 | alphafold | PREDICTED | 84.26 | — |
Amino-acid sequence (465 residues)
MAMTGSTPCS SMSNHTKERV TMTKVTLENF YSNLIAQHEE REMRQKKLEK VMEEEGLKDE EKRLRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKGHVKLSD FGLCTGLKKA HRTEFYRNLN HSLPSDFTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQTGYN KLCDWWSLGV IMYEMLIGYP PFCSETPQET YKKVMNWKET LTFPPEVPIS EKAKDLILRF CCEWEHRIGA PGVEEIKSNS FFEGVDWEHI RERPAAISIE IKSIDDTSNF DEFPESDILK PTVATSNHPE TDYKNKDWVF INYTYKRFEG LTARGAIPSY MKAAK
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