About Transmembrane emp24 domain-containing protein 2
Transmembrane emp24 domain-containing protein 2 (TMED2) is a protein
from Homo sapiens identified by UniProt accession
Q15363, 201 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Transmembrane emp24 domain-containing protein 2 |
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| UniProt accession | Q15363 |
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| Gene | TMED2 |
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| Organism | Homo sapiens |
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| Length | 201 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (48)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.56
- lysosomal storage disease · score 0.37
- breast adenocarcinoma · score 0.24
- pancreatic adenocarcinoma · score 0.23
- squamous cell lung carcinoma · score 0.18
- triglyceride measurement · score 0.15
- cutaneous melanoma · score 0.14
- lung adenocarcinoma · score 0.09
- cancer · score 0.08
- lymphocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15363-F1 | alphafold | PREDICTED | 87.04 | — |
Amino-acid sequence (201 residues)
MVTLAELLVL LAALLATVSG YFVSIDAHAE ECFFERVTSG TKMGLIFEVA EGGFLDIDVE ITGPDNKGIY KGDRESSGKY TFAAHMDGTY KFCFSNRMST MTPKIVMFTI DIGEAPKGQD METEAHQNKL EEMINELAVA MTAVKHEQEY MEVRERIHRA INDNTNSRVV LWSFFEALVL VAMTLGQIYY LKRFFEVRRV V
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