About Mitochondrial import receptor subunit TOM20 homolog
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) is a protein
from Homo sapiens identified by UniProt accession
Q15388, 145 residues long.
MolForge cross-references it against 0 known binders and
157 disease associations.
Target properties
| Protein name | Mitochondrial import receptor subunit TOM20 homolog |
|---|
| UniProt accession | Q15388 |
|---|
| Gene | TOMM20 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 145 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (157)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- monocyte count · score 0.24
- low density lipoprotein cholesterol measurement · score 0.23
- glioblastoma multiforme · score 0.23
- monocyte percentage of leukocytes · score 0.21
- apolipoprotein A 1 measurement · score 0.21
- platelet count · score 0.20
- serum alanine aminotransferase measurement · score 0.17
- high density lipoprotein cholesterol measurement · score 0.17
- total cholesterol measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15388-F1 | alphafold | PREDICTED | 76.43 | — |
Amino-acid sequence (145 residues)
MVGRNSAIAA GVCGALFIGY CIYFDRKRRS DPNFKNRLRE RRKKQKLAKE RAGLSKLPDL KDAEAVQKFF LEEIQLGEEL LAQGEYEKGV DHLTNAIAVC GQPQQLLQVL QQTLPPPVFQ MLLTKLPTIS QRIVSAQSLA EDDVE
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