Protein SSXT (SS18)

About Protein SSXT

Protein SSXT (SS18) is a protein from Homo sapiens identified by UniProt accession Q15532, 418 residues long. MolForge cross-references it against 0 known binders and 184 disease associations.

Target properties

Protein name	Protein SSXT
UniProt accession	Q15532
Gene	SS18
Organism	Homo sapiens
Length	418 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (184)

Diseases linked to this target (Open Targets).

synovial sarcoma · score 0.39
rhabdomyosarcoma · score 0.37
malignant peripheral nerve sheath tumor · score 0.37
Pleural Sarcomatoid Mesothelioma · score 0.37
Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor · score 0.37
monophasic synovial sarcoma · score 0.37
leiomyosarcoma · score 0.37
neurofibroma · score 0.37
Thyroid Gland Spindle Cell Tumor with Thymus-Like Differentiation · score 0.37
undifferentiated pleomorphic sarcoma · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15532-F1	alphafold	PREDICTED	53.70	—

Amino-acid sequence (418 residues)

MSVAFAAPRQ RGKGEITPAA IQKMLDDNNH LIQCIMDSQN KGKTSECSQY QQMLHTNLVY LATIADSNQN MQSLLPAPPT QNMPMGPGGM NQSGPPPPPR SHNMPSDGMV GGGPPAPHMQ NQMNGQMPGP NHMPMQGPGP NQLNMTNSSM NMPSSSHGSM GGYNHSVPSS QSMPVQNQMT MSQGQPMGNY GPRPNMSMQP NQGPMMHQQP PSQQYNMPQG GGQHYQGQQP PMGMMGQVNQ GNHMMGQRQI PPYRPPQQGP PQQYSGQEDY YGDQYSHGGQ GPPEGMNQQY YPDGHNDYGY QQPSYPEQGY DRPYEDSSQH YYEGGNSQYG QQQDAYQGPP PQQGYPPQQQ QYPGQQGYPG QQQGYGPSQG GPGPQYPNYP QGQGQQYGGY RPTQPGPPQP PQQRPYGYDQ GQYGNYQQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards