ELAV-like protein 1 (ELAVL1)

About ELAV-like protein 1

ELAV-like protein 1 (ELAVL1) is a protein from Homo sapiens identified by UniProt accession Q15717, 326 residues long. MolForge cross-references it against 0 known binders and 414 disease associations.

Target properties

Protein name	ELAV-like protein 1
UniProt accession	Q15717
Gene	ELAVL1
Organism	Homo sapiens
Length	326 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (414)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
neoplasm · score 0.12
cancer · score 0.11
triple-negative breast cancer · score 0.10
viral load · score 0.10
melanoma · score 0.10
gonorrhea · score 0.10
nail-patella syndrome · score 0.10
experimental autoimmune encephalomyelitis · score 0.10
chronic obstructive pulmonary disease · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15717-F1	alphafold	PREDICTED	79.82	—

Amino-acid sequence (326 residues)

MSNGYEDHMA EDCRGDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS LGYGFVNYVT AKDAERAINT LNGLRLQSKT IKVSYARPSS EVIKDANLYI SGLPRTMTQK DVEDMFSRFG RIINSRVLVD QTTGLSRGVA FIRFDKRSEA EEAITSFNGH KPPGSSEPIT VKFAANPNQN KNVALLSQLY HSPARRFGGP VHHQAQRFRF SPMGVDHMSG LSGVNVPGNA SSGWCIFIYN LGQDADEGIL WQMFGPFGAV TNVKVIRDFN TNKCKGFGFV TMTNYEEAAM AIASLNGYRL GDKILQVSFK TNKSHK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards