About Mitochondrial import receptor subunit TOM34
Mitochondrial import receptor subunit TOM34 (TOMM34) is a protein
from Homo sapiens identified by UniProt accession
Q15785, 309 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Mitochondrial import receptor subunit TOM34 |
|---|
| UniProt accession | Q15785 |
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| Gene | TOMM34 |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.08
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.08
- blood protein measurement · score 0.05
- acute myeloid leukemia · score 0.05
- platelet count · score 0.05
- mean platelet volume · score 0.05
- feeling "fed-up" measurement · score 0.03
- cancer · score 0.02
- colorectal cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15785-F1 | alphafold | PREDICTED | 87.79 | — |
Amino-acid sequence (309 residues)
MAPKFPDSVE ELRAAGNESF RNGQYAEASA LYGRALRVLQ AQGSSDPEEE SVLYSNRAAC HLKDGNCRDC IKDCTSALAL VPFSIKPLLR RASAYEALEK YPMAYVDYKT VLQIDDNVTS AVEGINRMTR ALMDSLGPEW RLKLPSIPLV PVSAQKRWNS LPSENHKEMA KSKSKETTAT KNRVPSAGDV EKARVLKEEG NELVKKGNHK KAIEKYSESL LCSNLESATY SNRALCYLVL KQYTEAVKDC TEALKLDGKN VKAFYRRAQA HKALKDYKSS FADISNLLQI EPRNGPAQKL RQEVKQNLH
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