About Protein SSX1
Protein SSX1 (SSX1) is a protein
from Homo sapiens identified by UniProt accession
Q16384, 188 residues long.
MolForge cross-references it against 0 known binders and
138 disease associations.
Target properties
| Protein name | Protein SSX1 |
| UniProt accession | Q16384 |
| Gene | SSX1 |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (138)
Diseases linked to this target (Open Targets).
- synovial sarcoma · score 0.38
- rhabdomyosarcoma · score 0.37
- malignant peripheral nerve sheath tumor · score 0.37
- leiomyosarcoma · score 0.37
- neurofibroma · score 0.37
- plexiform neurofibroma · score 0.37
- lung carcinoma · score 0.37
- liposarcoma · score 0.37
- monophasic synovial sarcoma · score 0.37
- Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q16384-F1 | alphafold | PREDICTED | 68.56 | — |
Amino-acid sequence (188 residues)
MNGDDTFAKR PRDDAKASEK RSKAFDDIAT YFSKKEWKKM KYSEKISYVY MKRNYKAMTK LGFKVTLPPF MCNKQATDFQ GNDFDNDHNR RIQVEHPQMT FGRLHRIIPK IMPKKPAEDE NDSKGVSEAS GPQNDGKQLH PPGKANISEK INKRSGPKRG KHAWTHRLRE RKQLVIYEEI SDPEEDDE
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