About Protein SSX2
Protein SSX2 (SSX2) is a protein
from Homo sapiens identified by UniProt accession
Q16385, 188 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Protein SSX2 |
|---|
| UniProt accession | Q16385 |
|---|
| Gene | SSX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 188 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- synovial sarcoma · score 0.37
- Extraskeletal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor · score 0.37
- neurofibroma · score 0.37
- liposarcoma · score 0.37
- monophasic synovial sarcoma · score 0.37
- rhabdomyosarcoma · score 0.37
- malignant peripheral nerve sheath tumor · score 0.37
- leiomyosarcoma · score 0.37
- plexiform neurofibroma · score 0.37
- Pleural Sarcomatoid Mesothelioma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16385-F1 | alphafold | PREDICTED | 68.55 | — |
Amino-acid sequence (188 residues)
MNGDDAFARR PTVGAQIPEK IQKAFDDIAK YFSKEEWEKM KASEKIFYVY MKRKYEAMTK LGFKATLPPF MCNKRAEDFQ GNDLDNDPNR GNQVERPQMT FGRLQGISPK IMPKKPAEEG NDSEEVPEAS GPQNDGKELC PPGKPTTSEK IHERSGPKRG EHAWTHRLRE RKQLVIYEEI SDPEEDDE
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