Lymphocyte antigen 6E (LY6E)

About Lymphocyte antigen 6E

Lymphocyte antigen 6E (LY6E) is a protein from Homo sapiens identified by UniProt accession Q16553, 131 residues long. MolForge cross-references it against 0 known binders and 162 disease associations.

Target properties

Protein name	Lymphocyte antigen 6E
UniProt accession	Q16553
Gene	LY6E
Organism	Homo sapiens
Length	131 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (162)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.08
neoplasm · score 0.07
cancer · score 0.06
hypertrophic cardiomyopathy · score 0.06
dilated cardiomyopathy · score 0.05
dilated cardiomyopathy 1M · score 0.04
dilated cardiomyopathy 2A · score 0.04
left ventricular noncompaction · score 0.04
Systemic lupus erythematosus · score 0.04
Sensorineural deafness with dilated cardiomyopathy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16553-F1	alphafold	PREDICTED	77.59	—

Amino-acid sequence (131 residues)

MKIFLPVLLA ALLGVERASS LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF SAADGGLRAS VTLLGAGLLL SLLPALLRFG P

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards