About Serine/arginine-rich splicing factor 7
Serine/arginine-rich splicing factor 7 (SRSF7) is a protein
from Homo sapiens identified by UniProt accession
Q16629, 238 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Serine/arginine-rich splicing factor 7 |
|---|
| UniProt accession | Q16629 |
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| Gene | SRSF7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 238 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- chronic lymphocytic leukemia · score 0.23
- glioblastoma multiforme · score 0.07
- body height · score 0.06
- blood protein measurement · score 0.05
- hepatocellular carcinoma · score 0.05
- lymphocyte count · score 0.04
- protein measurement · score 0.04
- cancer · score 0.04
- type 1 diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16629-F1 | alphafold | PREDICTED | 57.91 | — |
Amino-acid sequence (238 residues)
MSRYGRYGGE TKVYVGNLGT GAGKGELERA FSYYGPLRTV WIARNPPGFA FVEFEDPRDA EDAVRGLDGK VICGSRVRVE LSTGMPRRSR FDRPPARRPF DPNDRCYECG EKGHYAYDCH RYSRRRRSRS RSRSHSRSRG RRYSRSRSRS RGRRSRSASP RRSRSISLRR SRSASLRRSR SGSIKGSRYF QSPSRSRSRS RSISRPRSSR SKSRSPSPKR SRSPSGSPRR SASPERMD
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