About Synaptotagmin-16
Synaptotagmin-16 (SYT16) is a protein
from Homo sapiens identified by UniProt accession
Q17RD7, 645 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Synaptotagmin-16 |
|---|
| UniProt accession | Q17RD7 |
|---|
| Gene | SYT16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 645 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- body mass index · score 0.40
- body fat percentage · score 0.40
- body weight · score 0.36
- chronotype measurement · score 0.33
- fat body mass · score 0.32
- Hepatitis · score 0.30
- visceral adipose tissue measurement · score 0.28
- drug use measurement · score 0.27
- body height · score 0.26
- serum alanine aminotransferase measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q17RD7-F1 | alphafold | PREDICTED | 60.24 | — |
Amino-acid sequence (645 residues)
MVLAMASQDV QNFFQPFSSW ISRVYEALQQ AGDMLSASLV NISKQDSKLS DKLDQDLDNI QIQETYFEDE EQDNDWSQED ANSLFLEVDH FSCCNSDLQD SAQNSSPSLS QHAKDSCSTM SQWPNWASDD RKLPHVLSSI AEEEHHLEKQ RSGLQHGFDS QLPGTLETVN GKKQVNSFGD DEELSTSSDS DEEVIKQFEI SVSRSQSFRS VTSEKGKQTG LEQKPKFSRS LLTHGEDGTE VSACEDLDGA SQRRYSENLS YGEDDHIPAH SQSPCERGDA KHHGTSHQES SVVQSLRRQS TEGSLEMETA FNSRGFEDSY ATDSSSMWSP EEQDRTNLQV PSGVSEPISK CGDLDVIFEY RAASQKLTVT IVRAQGLPDK DRSGVNSWQV HVVLLPGKKH RGRTNIQRGP NPVFREKVTF AKLEPRDVAA CAVRFRLYAA RKMTRERMMG EKLFYLSHLH PEGEMKVTLV LEPRSNISSG GSPLSPSAVS HSDSTSSTQS LSHGGAPELL VGLSYNATTG RLSVEMIKGS HFRNLAVNRA PDTYGKLFLL NSVGQEMSRC KTSIRRGQPN PVYKETFVFQ VALFQLSDVT LMISVYNRRT MKRKEMIGWI ALGQNSSGEE EQDHWEEMKE TKGQQICRWH TLLES
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