About Lymphocyte antigen 6K
Lymphocyte antigen 6K (LY6K) is a protein
from Homo sapiens identified by UniProt accession
Q17RY6, 165 residues long.
MolForge cross-references it against 0 known binders and
135 disease associations.
Target properties
| Protein name | Lymphocyte antigen 6K |
| UniProt accession | Q17RY6 |
| Gene | LY6K |
| Organism | Homo sapiens |
| Length | 165 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- serum albumin measurement · score 0.13
- optic disc size measurement · score 0.12
- body fat percentage · score 0.12
- urinary bladder cancer · score 0.12
- urinary bladder carcinoma · score 0.10
- fat body mass · score 0.10
- azoospermia · score 0.08
- calcium measurement · score 0.08
- cancer · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q17RY6-F1 | alphafold | PREDICTED | 72.84 | — |
Amino-acid sequence (165 residues)
MALLALLLVV ALPRVWTDAN LTARQRDPED SQRTDEGDNR VWCHVCEREN TFECQNPRRC KWTEPYCVIA AVKIFPRFFM VAKQCSAGCA AMERPKPEEK RFLLEEPMPF FYLKCCKIRY CNLEGPPINS SVFKEYAGSM GESCGGLWLA ILLLLASIAA GLSLS
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