UDP-N-acetylglucosamine transporter SLC35D4 (SLC35D4)

About UDP-N-acetylglucosamine transporter SLC35D4

UDP-N-acetylglucosamine transporter SLC35D4 (SLC35D4) is a protein from Homo sapiens identified by UniProt accession Q24JQ0, 296 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	UDP-N-acetylglucosamine transporter SLC35D4
UniProt accession	Q24JQ0
Gene	SLC35D4
Organism	Homo sapiens
Length	296 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

worry measurement · score 0.37
platelet count · score 0.34
triglyceride measurement · score 0.33
osteoarthritis · score 0.30
waist circumference · score 0.23
body weights and measures · score 0.13
body height · score 0.12
genetic disorder · score 0.12
waist-hip ratio · score 0.07
isolated asymptomatic elevation of creatine phosphokinase · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q24JQ0-F1	alphafold	PREDICTED	94.11	—

Amino-acid sequence (296 residues)

MCVRRSLVGL TFCTCYLASY LTNKYVLSVL KFTYPTLFQG WQTLIGGLLL HVSWKLGWVE INSSSRSHVL VWLPASVLFV GIIYAGSRAL SRLAIPVFLT LHNVAEVIIC GYQKCFQKEK TSPAKICSAL LLLAAAGCLP FNDSQFNPDG YFWAIIHLLC VGAYKILQKS QKPSALSDID QQYLNYIFSV VLLAFASHPT GDLFSVLDFP FLYFYRFHGS CCASGFLGFF LMFSTVKLKN LLAPGQCAAW IFFAKIITAG LSILLFDAIL TSATTGCLLL GALGEALLVF SERKSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards