Beta-defensin 110 (DEFB110)

Homo sapiens — UniProt Q30KQ9

Gene: DEFB110Homo sapiensSwissProt reviewed

About Beta-defensin 110

Beta-defensin 110 (DEFB110) is a protein from Homo sapiens identified by UniProt accession Q30KQ9, 67 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein nameBeta-defensin 110
UniProt accessionQ30KQ9
GeneDEFB110
OrganismHomo sapiens
Length67 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • lung adenocarcinoma · score 0.24
  • cutaneous melanoma · score 0.23
  • glioblastoma multiforme · score 0.20
  • ovarian cancer · score 0.18
  • squamous cell lung carcinoma · score 0.17
  • gastric adenocarcinoma · score 0.14
  • spinal cord disease · score 0.10
  • glucuronate measurement · score 0.10
  • body mass index · score 0.08
  • cardiovascular disease · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q30KQ9-F1alphafoldPREDICTED80.61—

Amino-acid sequence (67 residues)

MKIQLFFFIL HFWVTILPAK KKYPEYGSLD LRRECRIGNG QCKNQCHENE IRIAYCIRPG THCCLQQ

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Quick facts

UniProtQ30KQ9
GeneDEFB110
OrganismHomo sapiens
Length67
Binders0
Diseases19
View on UniProt