About Protein-glucosylgalactosylhydroxylysine glucosidase
Protein-glucosylgalactosylhydroxylysine glucosidase (PGGHG) is a protein
from Homo sapiens identified by UniProt accession
Q32M88, 737 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Protein-glucosylgalactosylhydroxylysine glucosidase |
|---|
| UniProt accession | Q32M88 |
|---|
| Gene | PGGHG |
|---|
| Organism | Homo sapiens |
|---|
| Length | 737 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.26
- reticulocyte count · score 0.10
- mean platelet volume · score 0.08
- blood protein measurement · score 0.08
- liver fibrosis measurement · score 0.07
- hematocrit · score 0.06
- hemoglobin measurement · score 0.05
- total blood protein measurement · score 0.05
- FEV/FVC ratio · score 0.05
- mitochondrial DNA measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q32M88-F1 | alphafold | PREDICTED | 91.27 | — |
Amino-acid sequence (737 residues)
MEDAGEDPTT FAAHSLPSDP RLLATVTNAY LGTRVFHDTL HVSGVYNGAG GDTHRAMLPS PLNVRLEAPA GMGEQLTETF ALDTNTGSFL HTLEGPRFRA SQCIYAHRTL PHVLAFRVSI ARLAPGSGPI TLLLRSAFSP ESPDLDLHQG PDFQGARYLY GHTLTPEQPG GPQQEVHMLW TPAPPDLTLG EGEEARTWDF LTAVGGSQAE AQACLTEALQ LQARGALYTA HAQAWAQLWV ECGLDVVGPL QLRQALRGSL YYLLSALPQP KAPGYICHGL SPGGLSNGSR EECYWGHVFW DQDLWMFPSI LMFHPEAARA ILEYRIRTLD GALENAQNLG YQGAKFAWES ADSGLEVCPE DIYGVQEVHV NGAVVLAFEL YYHTTQDLQL FREAGGWDVV RAVAEFWCSR VEWSPREEKY HLRGVMSPDE YHSGVNNSVY TNVLVQNSLR FAAALAQDLG LPIPSQWLAV ADKIKVPFDV EQNFHPEFDG YEPGEVVKQA DVVLLGYPVP FSLSPDVRRK NLEIYEAVTS PQGPAMTWSM FAVGWMELKD AVRARGLLDR SFANMAEPFK VWTENADGSG AVNFLTGMGG FLQAVVFGCT GFRVTRAGVT FDPVCLSGIS RVSVSGIFYQ GNKLNFSFSE DSVTVEVTAR AGPWAPHLEA ELWPSQSRLS LLPGHKVSFP RSAGRIQMSP PKLPGSSSSE FPGRTFSDVR DPLQSPLWVT LGSSSPTESL TVDPASE
Explore Protein-glucosylgalactosylhydroxylysine glucosidase with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets