Protein BEAN1 (BEAN1)

Homo sapiens — UniProt Q3B7T3

Gene: BEAN1Homo sapiensSwissProt reviewed

About Protein BEAN1

Protein BEAN1 (BEAN1) is a protein from Homo sapiens identified by UniProt accession Q3B7T3, 259 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein nameProtein BEAN1
UniProt accessionQ3B7T3
GeneBEAN1
OrganismHomo sapiens
Length259 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (53)

Diseases linked to this target (Open Targets).

  • spinocerebellar ataxia type 31 · score 0.50
  • neurofibrillary tangles measurement · score 0.30
  • adolescent idiopathic scoliosis · score 0.10
  • FEV/FVC ratio · score 0.09
  • Benign familial chorea · score 0.07
  • response to risperidone · score 0.07
  • depressive symptom measurement · score 0.07
  • Tourette syndrome · score 0.07
  • unipolar depression · score 0.07
  • attention deficit hyperactivity disorder · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q3B7T3-F1alphafoldPREDICTED58.80—

Amino-acid sequence (259 residues)

MSFKRPCPLA RYNRTSYFYP TFSESSEHSH LLVSPVLVAS AVIGVVIILS CITIIVGSIR RDRQARLQRH RHRHHRHHHH HHHHRRRRHR EYEHGYVSDE HTYSRSSRRM RYACSSSEDW PPPLDISSDG DVDATVLREL YPDSPPGYEE CVGPGATQLY VPTDAPPPYS LTDSCPTLDG TSDSGSGHSP GRHQQEQRTP AQGGLHTVSM DTLPPYEAVC GAGPPSGLLP LPGPDPGPRG SQGSPTPTRA PASGPERIV

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Quick facts

UniProtQ3B7T3
GeneBEAN1
OrganismHomo sapiens
Length259
Binders0
Diseases53
View on UniProt