About NBPF family member NBPF1
NBPF family member NBPF1 (NBPF1) is a protein
from Homo sapiens identified by UniProt accession
Q3BBV0, 1214 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | NBPF family member NBPF1 |
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| UniProt accession | Q3BBV0 |
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| Gene | NBPF1 |
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| Organism | Homo sapiens |
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| Length | 1214 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (37)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.09
- body mass index · score 0.08
- cancer · score 0.08
- adrenal cortex carcinoma · score 0.07
- neuroblastoma · score 0.05
- lung adenocarcinoma · score 0.04
- erythrocyte count · score 0.03
- red blood cell density measurement · score 0.03
- body height · score 0.03
- systemic scleroderma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3BBV0-F1 | alphafold | PREDICTED | 47.23 | — |
Amino-acid sequence (1214 residues)
MVVSAGPWSS EKAETNILEI NEKLRPQLAE NKQQFRNLKE KCFVTQLAGF LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH SQERELTQLR EKLREGRDAS RSLNQHLQAL LTPDKPDKSQ GQDLQEQLAE GCRLAQQLFQ KLSPENDEDE DEDVQVEEAE KVLESSAPRE VQKAEESKVP EDSLEECAIT CSNSHSPCDS NQPHKNINIT FEEDKVNSTL VVDRESSHDE CQDAVNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLHPQLA EKKQQFRNLK EKCFVTQLAC FLANQQNKYK YEECKDLIKS MLRNERQFKE EKLAEQLKQA EELRQYKVLV HSQERELTQL REKLREGRDA SRSLNQHLQA LLTPDKPDKS QGQDLQEQLA EGCRLAQQLF QKLSPENDED EDEDVQVEEA EKVLESSAPR EVQKAEESKV PEDSLEECAI TCSNSHGPCD SNQPHKNINI TFEEDKVNSA LVVDRESSHD ECQDAVNILP VPGPTSSATN VSMVVSAGPL SSEKAEMNIL EINEKLHPQL AEKKQQFRNL KEKCFVTQLA CFLANQQNKY KNEECKDLIK SMLRNERQFK EEKLAEQLKQ AEELRQYKVL VHSQERELTQ LREKLREGRD ASCSLNQHLQ ALLTPDEPDK SQGQDLQEQL AEGCRLAQHL VQKLSPENDN DDDEDVQVEV AEKVQKSSAP REMPKAEEKE VPEDSLEECA ITCSNSHGPY DSNQPHRKTK ITFEEDKVDS TLIGSSSHVE WEDAVHIIPE NESDDEEEEE KGPVSPRNLQ ESEEEEVPQE SWDEGYSTLS IPPEMLASYK SYSGTFHSLE EQQVCMAVDI GGHRWDQVKK EDQEATGPRL SRELLDEKGP EVLQDSLDRC YSTPSGYLEL TDSCQPYRSA FYILEQQRVG WALDMDEIEK YQEVEEDQDP SCPRLSRELL DEKEPEVLQD SLDRCYSTPS GYLELPDLGQ PYRSAVYSLE EQYLGLALDV DRIKKDQEEE EDQGPPCPRL SRELLEAVEP EVLQDSLDRC YSTPSSCLEQ PDSCLPYGSS FYALEEKHVG FSLDVGEIEK KGKGKKRRGR RSTKKRRRRG RKEGEEDQNP PCPRLSGMLM EVEEPEVLQD SLDRCYSTPS MYFELPDSFQ HYRSVFYSFE EQHISFALDV DNRFLTLMGT SLHLVFQMGV IFPQ
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