Membrane-spanning 4-domains subfamily A member 18…

About Membrane-spanning 4-domains subfamily A member 18

Membrane-spanning 4-domains subfamily A member 18 (MS4A18) is a protein from Homo sapiens identified by UniProt accession Q3C1V0, 398 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Membrane-spanning 4-domains subfamily A member 18
UniProt accession	Q3C1V0
Gene	MS4A18
Organism	Homo sapiens
Length	398 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

psoriasis · score 0.02
Crohn's disease · score 0.02
gastric cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3C1V0-F1	alphafold	PREDICTED	53.88	—

Amino-acid sequence (398 residues)

MTEQVIGANS VPGIIAPDNV HVIQPSNPVA SGNHLQPSEV TTYPISPKVI HCDTGRANLQ NLLVVNQNSA AGVQSQPIGY QRQYPVGTAS LQTVPGVIQY TQGTTNLQTW PGDLQNPLNA NPGLTHTSNS SQWNTSFASF TSFNPKKFIN EEVRTLGAIQ ILIGLTHIFS AINPVLYYYP FVTWLSGYPL WGGLSYIVSG SLSVWAAKDP SPCVVNSSIS FNIISALFAF AGIFIIITDL SLYYVTTYSK AVSGGLLPFA LLEFILTCVV SHFGCQATCC RQFENVAVIP TVFSFNPANT TTSPVNATTG PVNAATGPVS ATNGPVNTTI HPVNTTTSPV NTTTSPVNVT TGPVNANIGP VNVTTGPVNT TTAPAKATTS CVNAIHTSNV PPNPRTKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Membrane-spanning 4-domains subfamily A member 18 (MS4A18)