About Brain-specific homeobox protein homolog
Brain-specific homeobox protein homolog (BSX) is a protein
from Homo sapiens identified by UniProt accession
Q3C1V8, 233 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Brain-specific homeobox protein homolog |
|---|
| UniProt accession | Q3C1V8 |
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| Gene | BSX |
|---|
| Organism | Homo sapiens |
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| Length | 233 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- body height · score 0.28
- age at menarche · score 0.23
- chronotype measurement · score 0.16
- puberty onset measurement · score 0.14
- sleep duration · score 0.12
- adolescent idiopathic scoliosis · score 0.11
- heart failure · score 0.10
- coronary artery disease · score 0.10
- atrial fibrillation · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3C1V8-F1 | alphafold | PREDICTED | 67.90 | — |
Amino-acid sequence (233 residues)
MNLNFTSPLH PASSQRPTSF FIEDILLHKP KPLREVAPDH FASSLASRVP LLDYGYPLMP TPTLLAPHAH HPLHKGDHHH PYFLTTSGMP VPALFPHPQH AELPGKHCRR RKARTVFSDS QLSGLEKRFE IQRYLSTPER VELATALSLS ETQVKTWFQN RRMKHKKQLR KSQDEPKAPD GPESPEGSPR GSEAATAAEA RLSLPAGPFV LTEPEDEVDI GDEGELGSGP HVL
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