About Protein LSM12
Protein LSM12 (LSM12) is a protein
from Homo sapiens identified by UniProt accession
Q3MHD2, 195 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Protein LSM12 |
|---|
| UniProt accession | Q3MHD2 |
|---|
| Gene | LSM12 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 195 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- body height · score 0.11
- oral squamous cell carcinoma · score 0.07
- axial length measurement · score 0.07
- neoplasm · score 0.07
- heel bone mineral density · score 0.06
- mean corpuscular volume · score 0.04
- sex hormone-binding globulin measurement · score 0.04
- urate measurement · score 0.04
- bone density · score 0.03
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3MHD2-F1 | alphafold | PREDICTED | 90.65 | — |
Amino-acid sequence (195 residues)
MAAPPGEYFS VGSQVSCRTC QEQRLQGEVV AFDYQSKMLA LKCPSSSGKP NHADILLINL QYVSEVEIIN DRTETPPPLA SLNVSKLASK ARTEKEEKLS QAYAISAGVS LEGQQLFQTI HKTIKDCKWQ EKNIVVMEEV VITPPYQVEN CKGKEGSALS HVRKIVEKHF RDVESQKILQ RSQAQQPQKE AALSS
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