Cell cycle control protein 50B (TMEM30B)

About Cell cycle control protein 50B

Cell cycle control protein 50B (TMEM30B) is a protein from Homo sapiens identified by UniProt accession Q3MIR4, 351 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Cell cycle control protein 50B
UniProt accession	Q3MIR4
Gene	TMEM30B
Organism	Homo sapiens
Length	351 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

hair shape measurement · score 0.17
balding measurement · score 0.13
PHF-tau measurement · score 0.09
obesity · score 0.08
adolescent idiopathic scoliosis · score 0.06
lymphocyte count · score 0.06
Down syndrome · score 0.05
rheumatoid arthritis · score 0.04
clear cell renal carcinoma · score 0.04
uncombable hair syndrome · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3MIR4-F1	alphafold	PREDICTED	92.18	—

Amino-acid sequence (351 residues)

MTWSATARGA HQPDNTAFTQ QRLPAWQPLL SASIALPLFF CAGLAFIGLG LGLYYSSNGI KELEYDYTGD PGTGNCSVCA AAGQGRALPP PCSCAWYFSL PELFQGPVYL YYELTNFYQN NRRYGVSRDD AQLSGLPSAL RHPVNECAPY QRSAAGLPIA PCGAIANSLF NDSFSLWHQR QPGGPYVEVP LDRSGIAWWT DYHVKFRNPP LVNGSLALAF QGTAPPPNWR RPVYELSPDP NNTGFINQDF VVWMRTAALP TFRKLYARIR QGNYSAGLPR GAYRVNITYN YPVRAFGGHK LLIFSSISWM GGKNPFLGIA YLVVGSLCIL TGFVMLVVYI RYQDQDDDDE E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards