Membrane protein FAM174B (FAM174B)

About Membrane protein FAM174B

Membrane protein FAM174B (FAM174B) is a protein from Homo sapiens identified by UniProt accession Q3ZCQ3, 159 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Membrane protein FAM174B
UniProt accession	Q3ZCQ3
Gene	FAM174B
Organism	Homo sapiens
Length	159 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

pilocytic astrocytoma · score 0.37
systolic blood pressure · score 0.37
prostate adenocarcinoma · score 0.32
pulse pressure measurement · score 0.31
medulloblastoma · score 0.17
gut microbiome measurement · score 0.17
drug use measurement · score 0.02
chronic interstitial cystitis · score 0.01
chronic lymphocytic leukemia · score 0.01
psoriasis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3ZCQ3-F1	alphafold	PREDICTED	63.58	—

Amino-acid sequence (159 residues)

MRAVPLPAPL LPLLLLALLA APAARASRAE SVSAPWPEPE RESRPPPGPG PGNTTRFGSG AAGGSGSSSS NSSGDALVTR ISILLRDLPT LKAAVIVAFA FTTLLIACLL LRVFRSGKRL KKTRKYDIIT TPAERVEMAP LNEEDDEDED STVFDIKYR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards