About Archaemetzincin-1
Archaemetzincin-1 (AMZ1) is a protein
from Homo sapiens identified by UniProt accession
Q400G9, 498 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Archaemetzincin-1 |
|---|
| UniProt accession | Q400G9 |
|---|
| Gene | AMZ1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 498 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- body height · score 0.45
- protein measurement · score 0.41
- birth weight · score 0.40
- appendicular lean mass · score 0.38
- lymphocyte count · score 0.36
- monocyte count · score 0.31
- parental genotype effect measurement · score 0.30
- leukocyte count · score 0.29
- chronic obstructive pulmonary disease · score 0.28
- type 2 diabetes mellitus · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q400G9-F1 | alphafold | PREDICTED | 73.45 | — |
Amino-acid sequence (498 residues)
MLQCRPAQEF SFGPRALKDA LVSTDAALQQ LYVSAFSPAE RLFLAEAYNP QRTLFCTLLI RTGFDWLLSR PEAPEDFQTF HASLQHRKPR LARKHIYLQP IDLSEEPVGS SLLHQLCSCT EAFFLGLRVK CLPSVAAASI RCSSRPSRDS DRLQLHTDGI LSFLKNNKPG DALCVLGLTL SDLYPHEAWS FTFSKFLPGH EVGVCSFARF SGEFPKSGPS APDLALVEAA ADGPEAPLQD RGWALCFSAL GMVQCCKVTC HELCHLLGLG NCRWLRCLMQ GALSLDEALR RPLDLCPICL RKLQHVLGFR LIERYQRLYT WTQAVVGTWP SQEAGEPSVW EDTPPASADS GMCCESDSEP GTSVSEPLTP DAGSHTFASG PEEGLSYLAA SEAPLPPGGP AEAIKEHERW LAMCIQALQR EVAEEDLVQV DRAVDALDRW EMFTGQLPAT RQDPPSSRDS VGLRKVLGDK FSSLRRKLSA RKLARAESAP RPWDGEES
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